Olga Obukhova
Moscow, NN Blokhin NMRCO, Russian FederationTitle : The Nutritional Status of Oncological Patient Prior to Antitumor Treatment: Single-Center Prospective Observational Study
Abstract
Malnutrition is a frequent medical problem of cancer patients that negatively impacts of results of antitumor treatment. We investigated the problem of malnutrition in cancer hospital. Our study included 80 patients (30 males, 51.6±13.6 years) who underwent examination before antitumor treatment (medical/surgical). Body mass index (BMI), weight loss (WL) over last 6 months, decrease in appetite, reasons for decrease in food intake, physical activity, nosology, cancer staging, the time to diagnosis, total protein (TP), albumin, absolute lymphocyte count (ALC) were evaluated. According to our data, the BMI was 25.3±5.4 kg/m2, WL 9.0±0.1%. The most common pathology were esophageal/gastric cancer (31%), stage IV (77%). 25% had received treatment within the last 6–12 months, 60% had received chemotherapy. Only 13% had additionally used nutritional support (NS). An unwanted reduction of appetite was observed in 75% of patients. Most of them (34%) could not explain the reason of WL, 31% reported nausea/vomiting, 19% referred to anorexia; 13% had chemotherapy toxicity (dysgeusia, stomatitis), 3% could not eat properly due to the pain syndrome. Of 60 patients who lost weight, 54 (67.5%) had an average WL 14.1±9.1%. WL up to 5% was in 5 pts (6.25%), up to 10% in 14 patients (17.5%),35 (43.75%) — more than 10%. 46% retained their usual daily activity, 80% deemed it useful to include a NS in the treatment. The TP was 63.5±8.1 g/l, albumin 34.9±7.4 g/l, ALC 1.6±0.6×10(9)/l. ?hus, 6.25% were at the stage of precachexia, 61.25% already had cachexia. Although their compensatory capacity is quite high, the appointment of additional NS is an integral component of the management of these patients. Only one tenth of patients used some kind of NS. We deem, nutritional assessment should be mandatory in anticancer treatment.
Biography
Olga Obukhova has completed her
PhD at the age of 30 years at Pirogov Medical University, Moscow, Russian
Federation. She is the Head of Medical Rehabilitation at NN Blokhin NMRCO,
Russian Federation. She has 75 publications that have been cited 188 times, and
her publications h-index is 8. She is a member of the editorial board of the
Russian journal Clinical Nutrition and Metabolism.
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