Virtual Conference
Nutrition 2022

Irit Rutman- Halili

Hemdat Hadarom Academic College of Education, Israel

Title: The Inhibitory Effect of Caffeine on Starch Digestion


Caffeine is a natural compound found in a number of plant species including coffee, tea and cocoa. It is a central nervous system stimulant of the methylxanthine  class, and is probably the world's most widely consumed psychoactive drug. However, unlike many other psychoactive substances, it is legal and unregulated in nearly all parts of the world. While the ingestion of caffeine in the form of common beverages such as coffee and tea was previously considered to have the potential for causing harmful effects (particularly at higher doses), recent studies have provided evidence of several health benefits. Alpha-amylase is the major form of amylase in humans.   It hydrolyses alpha bonds of large, alpha-linked polysaccharides such as starch and glycogen,  and plays an important role in the digestion and metabolism of dietary carbohydrates. Recent studies have reported that caffeine alters saliva alpha amylase activity.  However, the nature of this alteration is still not clear.  Some studies reported    that caffeine increased saliva alpha amylase activity, while, in contrast, others have shown it to inhibit the enzyme.
The aim of this study was to further  investigate the effects of caffeine on the activity of isolated alpha amylase activity, using a spectrophotometric method.
It was found that caffeine significantly reduced alpha amylase activity in a dose-dependent manner.


Irit Rutman Halili completed her PHD at the age of 36 years at Bar-Ilan University, Israel. She is a senior lecturer at the Department of Science Education of the Hemdat Hadarom Academic College of Education, Israel, and also a director of research cooperation between the Katif Research Centre and the college. She has published her research findings in publications in a variety of research disciplines.