Virtual Conference
Nutrition 2022

Karina Al Assal

University of Sao Paulo,, Brazil

Title: Diet, probiotics and obese gut microbiota


The gut microbiome plays an important role in human health and influences the development of chronic diseases ranging from metabolic disease such obesity, type 2 diabetes, to metabolic syndrome etc. The gut microbiota provide unique metabolic functions to the host and are fundamentally important in health and disease. Dietary patterns, probiotics and environmental factors have a profound effect on shaping gut microbiota in real time. Diet is the most effective way to modulate the gut microbiota. Dietary fiber through the fermentation from intestinal bacterias produce short-chain fatty acids (SCFAs) and they act on the host metabolism, as endogenous signals with important roles in lipid homeostasis, satiety, glycemic control  and reducing inflammation. Probiotics and their metabolites also can alter the population composition of gut bacterial species that can, in turn, alter the fermentation metabolites, particularly SCFAs. Numerous bioactive dietary components, namely curcumin (turmeric), genistein (some pulses and soybean), garlic acid, ellagic acid, epigallocatechin-3-gallate, polyphenols, resveratrol (e.g. tea, some vegetables and fruits), and their gut metabolites interact with the cellular genome and metabolome of the host. The aim of this presentation is to explore the  gut microbiota from obese patients and how we can modulate with diet and probiotics in clinical practice 


Nutritionist. Co-founder at Bio Sukkar; Author and speaker: Personalized Nutrition, gut microbiota, metagenomics with the focus on clinical practice. Author of the paper Gut Microbiota Profile of Obese Diabetic Women Submitted to Roux-en-Y Gastric Bypass and Its Association with Food Intake and Postoperative Diabetes Remission. Nutrients. 2020 Jan 21;12(2). doi: 10.3390/nu12020278. Co-author of the book (only in Portuguese), published in Brazil:  “Reprogramando seu intestino” (2019).