Virtual Conference
Nutrition 2022

Noushin Mohammadifard

Isfahan University of Medical Sciences, Iran

Title: Association of plant-based diet index with anxiety and depression: Results from a multicentric community trial (LIPOKAP Study)


Dietary patterns emphasizing plant foods might be neuroprotective and exert health benefits on mental health; however, data are scarce on the association between a plant-based dietary index (PDI) and mental health measures. The current study was conducted to determine the association between three versions of PDI and depression and anxiety in a large national-representative sample of Iranian adults. This cross-sectional study was performed in a sample of 2033 participants. A validated food frequency questionnaire was used to evaluate dietary intakes of participants. Three versions of PDI including an overall PDI, a healthy PDI (hPDI), and an unhealthful PDI (uPDI) were created. The presence of anxiety and depression was examined via a validated Iranian version of the Hospital Anxiety and Depression Scale (HADS). PDI and hPDI were not pertinent to depression and anxiety after adjustment for potential covariates. However, in the crude model, the highest adherence to the uPDI approximately doubled the risk of depression (95% CI: 1.49, 2.87; P<0.0001) and increased the risk of anxiety by almost 50% (95% CI: 1.14, 2.14; P= 0.001). Adjustment for potential confounders just slightly changed the associations (OR for depression in the fourth quartile= 1.96; 95% CI: 1.34, 2.85, and OR for anxiety in the fourth quartile= 1.53; 95% CI: 1.07, 2.19). An uPDI is associated with a higher risk of depression and anxiety, while PDI and hPDI do not pertain to depression and anxiety.


Dr. Noushin Mohammadifard is an Assistant Professor and Head of Nutrition Department at the Cardiovascular Research Institute, Isfahan University of Medical Sciences, Iran (a WHO Collaborating Center in Eastern Mediterranean Region for Cardiovascular Disease (CVD) Prevention and Control). She is a Research Deputy of Isfahan Cardiovascular Research Institute in this Institute, as well. She earned her PhD in Nutrition Science from the Isfahan University of Medical Sciences, Iran. She has substantial expertise in nutrition epidemiology especially examining the impact of individual foods and dietary patterns on CVD outcomes and risk factors and also community interventional programs to improve nutrition for the prevention and control of CVDs. She has published more than 140 scientific papers in peer review journals regarding various aspects of diet and non-communicable diseases. She cooperated in writing and publishing three books. She is a Section Editor of Nutrition in Arya Atherosclerosis, an International Journal indexed in emerging sources citation index of Thomson Reuters ISI and editorial member and reviewers in several international journals.