Qinchuan Yang
Air Force Military Medical University, ChinaTitle: Protocol for feasibility and safety of adopting early oral feeding in post total laparoscopic total gastrectomy (overlap esophagojejunostomy): a multicenter randomized controlled trial
Abstract
A Gastric cancer remained the fifth most common cancer. Total
laparoscopic total gastrectomy (TLTG) for gastric cancer, especially with
overlap esophagojejunostomy, has been verified that it has advantages of
minimally invasion and faster recovery. Inevitably, total gastrectomy results
in the loss of the nutrient absorption function of the stomach, leading to
postoperative malnutrition.
Additionally, early oral feeding (EOF), as part of enhanced recovery
after surgery (ERAS), has shown beneficial clinical results after open
gastrectomy. On the other hand, oral nutritional supplements (ONS), as a form
of enteral nutrition, have attracted attention for its ability to reduce the
incidence of postoperative complications.
Regrettably, there is few related research proving whether it is
credible or safe to adopt EOF after TLTG (overlap esophagojejunostomy). We
planned to recruit 200 patients who were eligible for TLTG (100 in each group)
and randomly allocated into two different groups, including EOF group and delay
oral feeding (DOF) group after TLTG (overlap esophagojejunostomy).
Additionally, all groups were given ONS during the period oral feeding, in
addition to standard diet (or instead of being part of a normal diet).
Anastomotic leakage was recorded as the primary endpoints to ascertain the
feasibility and safety of adopting EOF after TLTG (overlap
esophagojejunostomy). This study is a prospective, multicenter, randomized
controlled trial. We implemented EOF protocol to evaluate the feasibility and
safety of adopting EOF after TLTG (overlap esophagojejunostomy), which provided
additional evidence for the development of clinical nutrition guidelines.
Biography
I have completed my
undergraduate studies at the age of 23 and received my Bachelor's degree from
Fourth Military Medical University. After graduation, I worked in a primary
health-care facility for 4 years. Now I am pursuing a Master's degree in
Surgery at the First Affiliated Hospital of the Air Force Military Medical
University in Xi'an, Shaanxi Province, China. My mentor is Professor Gang Ji
and academic advisor is Professor Xiaohua Li from Xijing hospital. I have been
involved in publishing 4 papers in reputable journals.
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