Xiaoyu Chen
Shanghai University of Medicine and Health Sciences, ChinaTitle: The Effects of Mobile-App-Based Low-Carbohydrate Dietary Guidance on Postprandial Hyperglycemia in Adults with Prediabetes
Abstract
Introduction: Postprandial hyperglycemia is
independently associated with many adverse
complications, while diets with a low glycemic
load are beneficial in improving post-meal glucose
levels. This study aims to determine if mobile-app-based low-carbohydrate dietary guidance will
reduce exposure to postprandial hyperglycemia in
adults with prediabetes.
Methods: This single-blind, randomized
controlled pilot study included 100 participants (39
men; mean age 53.6 ± 11.9 years) and was
performed in the PKU Care CNOOC Hospital,
China. The intervention group (n = 57) received
low-carbohydrate dietary guidance through a
moblie app (CAReNA) for 3 months, while the
control group (n = 43) only received health
education on a diabetic diet. The primary outcome
was change in time of postprandial hyperglycemia
between baseline and 3 months.
Results: The study revealed that the mean time in
postprandial hyperglycemia ([7.8 mmol/l [140
mg/dl]) monitored by flash glucose monitoring
changed from 3.27 h/day at baseline to 2.34 h/day
at 3 months in the intervention group and from
3.08 h/day to 2.96 h/day in the control group, with
a between-group difference of - 0.81 h/day (P <
0.05). Fasting plasma glucose and glycated
hemoglobin (HbA1c) in the intervention group
decreased significantly, although no significant
difference was seen between the two groups.
Compared with the control group, the intervention
group had a significant decrease in anthropometric
and body composition measurements as well as
triglycerides.
Conclusion: The mobile-app-based low-carbohydrate dietary guidance effectively reduced the
time spent in postprandial hyperglycemia in adults
with prediabetes. This new type of nutritional
management has beneficial effects on people with
prediabetes and needs further research.
Biography
Xiaoyu Chen has completed his PHD at the age of
27 years from Tianjin Medical University, China.
She has published 20 papers with a total IF score of
over 50; among them, she has published 9 papers
as the first author. She has published 6 monographs,
including 1 chief editor and 2 deputy chief editors.
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