Yang Yang
Zhejiang University, ChinaTitle: Can dental caries be an independent predictor of sarcopenia and its diagnostic factors?
Abstract
Epidemiological
studies have revealed the association of oral diseases with sarcopenia or its
diagnostic factors (low muscle strength, low muscle mass and reduced physical
performance). However, it remains unclear whether dental caries is an
independent predictor of sarcopenia or one of its diagnostic factors. Hence the
aim of this study was to investigate the associations of dental caries with
sarcopenia and its diagnostic factors. Method: This cross-sectional study
included a total of 1,961 participants aged 18-80. The Decayed, Missing, and
Filled teeth (DMFT) index was used for assessing severe dental caries. The
independent variables related to dental caries include DMFT index, severe
dental caries and tooth loss caused by caries. Severe dental caries was defined
as DMFT index over 8. Low muscle strength was assessed by hand grip force. Low
muscle mass was assessed by dual-energy X-ray absorptiometry (DXA) scan.
Sarcopenia was defined as the presence of both low muscle mass and low muscle
strength. Multivariate logistic regression models was used to analyse the
associations of dental caries with sarcopenia and its diagnostic factors.
Results: In the fully adjusted models, dental caries was positively associated
with sarcopenia (DMFT index: P-value=0.001; severe dental caries: odds
ratio[OR], 1.67; 95% confidence interval [CI], 1.13-2.46; tooth loss: P-value=0.002),
low muscle strength (DMFT index: P-value
Biography
Yang Yang is currently a direct application PhD Student at the department of Nutrition and Food Hygiene, Zhejiang University School of Public Health, under the supervision of Professor Shankuan Zhu. She did her undergraduate at Peking University from 2014-2018.
She is also in Shankuan Zhu's team at Chronic Disease Research Institute, Obesity and Body Composition Research Center at Zhejiang University School of Medicine, and Zhejiang University-Stanford University Collaborative Laboratory for Health. Her work focused specifically on obesity-related chronic diseases and body composition.
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