Natalia KhramtsovaE.A. Vagner Perm State Medical University, Russian Federation
Title: Malnutrition in patients with dysphagia: skinfolds measurement and BIA
Dysphagia leads to a deficiency of not only fat, but also muscles. Sarcopenia reduces survival and increases the risk of complications. Deficiency of fat in combination with sarcopenia reflects a pronounced nutritional deficiency. Sarcopenic obesity is a risk factor for the development of toxic complications during chemotherapy for esophageal cancer. In the same time, the increased body fat is sometimes referred to as a "paradoxical" predictor of better survival.
In 32 patients with dysphagia the body mass index, skinfolds thickness and body composition (BIA) were measured.
Patients with dysphagia were predominantly men (75%) of 59.8±13.0 years with dysphagia of 2 or 3 grade. The body mass index was 23.6±4.4 kg/m2. Body weight deficiency was determined in 7 (22%) patients.
A decrease in the thickness of skinfolds in the iliac region, on the anterior and posterior surfaces of the shoulder and lower leg were revealed. The skinfolds thickness correlated with body weight (R=0.6), body mass index (R=0.7) and fat content (R=0.5).
The fat content correlated with the body mass index (R=0.8) and amounted to 21.0±10.8%: normal - 44%, decreased - 28%, increased - 28%. In 19% the decrease of muscle mass was determined, only in cancer patients. The deficiency of fat in combination with sarcopenia was in 12.5% (21% - in cancer patients). Sarcopenic obesity was in 1 (5%) patient with esophageal cancer: muscle mass decrease with fat increase. In 3% fat increase in combination with a muscle mass decrease was found. Increased fat with normal muscle mass was in 31% of patients with benign strictures and in 16% with cancer. The body mass index correlated sufficiently only with adipose tissue percentage. The content of muscle mass did not sufficiently correlate with any of the anthropometric indicators. Bioimpedance analysis is recommended in malnutrition detection in patients with dysphagia.
Natalia Khramtsova has completed her PhD at the age of 28 years, and now finishing work on postdoc studies in E.A. Vagner Perm State Medical University, Russia. She is the head of the department of endoscopy. The has over 42 publications with 17 citations, 5 patents, 3 rationalization proposals, h-index is 2. She is a regular speaker at many International conferences of clinical medicine.