Sadia sultanFakeeh College for Medical Sciences, Saudi Arabia
Title: Neuroimaging changes associated with vitamin D Deficiency – a narrative review
Emerging evidence suggests the role of vitamin D in brain health and its implication in the pathogenesis of cognitive impairment. The Aim of this review is to summarize current evidence on neuroimaging changes seen in vitamin D deficient individuals. Cross-sectional and longitudinal studies have consistently found an association between low serum 25 hydroxyvitamin D and cognitive impairment. Furthermore, investigating the association between serum 25 hydroxyvitamin D and neuroimaging abnormalities could provide an insight into the potential mechanisms underlying the association with cognitive impairment. Animal studies have demonstrated structural changes in the cerebral cortex and hippocampus of vitamin D deficient mice. Neuroimaging studies of the brain have shown increased white matter hyperintensities in periventricular, cortical, and juxtacortical areas and grey matter atrophy of the hippocampus, anterior cingulate cortex, and left calcarine sulcus in elderly with vitamin D deficiency.
Dr. Sadia sultan is an MD in psychiatry and has worked as an assistant professor and Consultant at various hospitals and medical colleges in India and Saudi Arabia in her 12-year-old career. She is presently an assistant professor in the Clinical Sciences Department at Fakeeh College for Medical Sciences, Saudi Arabia. She was awarded a Certificate of Academic Excellence in the year 2012. She has a number of research papers to her name Her research interest is mainly neurocognitive disorders and she has three research papers related to this field. One of the research papers is related to Vitamin D deficiency and its association with cognitive impairment and another one is related to neuroimaging changes associated with vitamin D deficiency.